Forty Years of Solitude: Landmark Results from the S31/A5349 trial of Shortened Treatment for Drug-Susceptible Tuberculosis - Shared screen with speaker view
Who can see your viewing activity?
someone is making a lot of noise
Please mute all who are not speaking.
I think that attendees can’t speak anyway.
I believe it is the speaker's headset cable
her cable is not moving
when the noise is present
Alberto, there's some background static (intermittent). Is that from one of the mics?
i believe susan is brushing the cable to her headset when she's moving to forward slides? it's a guess.
I’m getting a lot of intermittent static - perhaps from he speaker’s mic itself. Perhaps someone could let her know?
Gustavo, if this persists, please let susan know about the disturbance
Alberto, some attendees are raising their hands to ask questions (e.g., Paul Sax). Are you able to unmute them or should we ask all questions come via chat?
OK. I think I saw Mary G. first, then Paul Sax
no, during Q&A at end
I will send out a message to attendees now
Attendees— the co-moderators and I will take questions via chat and can ask the presenters your questions, and for the two of you who have raised your hands we will call on you and unmute you if you want to speak. Thank you.
We’ll wait to take questions until after Dr. Chaisson’s talk.
Raj, I'll invite you to speak during the Q&A if OK with you and have a question
Galit, i'll invite you to speak during the Q&A if you wish and have a question
Hi Paul, I'll invite you to speak once we start the Q&A session. Are you ready?
Do you mean me? or a different Paul? This is a great series of talks!
Rocio, Amy— I can take the first question and call either on Paul or Raj to speak
I mean you, Paul Sax
unless you raised your hand by mistake
OK, I will call on Raj first and invite people to put questions in chat or raise their hands
OK, not problem
Raj I think Gustavo is going to call on you first if you have a question-
Gustavo before you call on Raj, do you want to remind people to post questions or raise their hands?
Yes will do
Thanks Gustavo and the organizers of this talk. First off - a serious congratulations to the team on this field-changing work. A couple questions for the authors if there is time:1. In thinking about how to convert these findings to practice in settings like SSA, how was DOT done in practice in the study - community/home-based or clinic-based? For the entire 4 month regimen?2. For relevance in the US (and hopefully one day SSA) are there data on bictegravir, doravarine with these regimens?
Rocio do you want to ask Mark
s questions next?
yes i can summarize and ask his questions
Congratulations on a terrific outcome! A question for any speaker. TB treatment programs have been critical for getting therapies to people. But they’re not famously flexible. Once the WHO endorses the therapy, how do you see implementation being carried out?
Great data, and wonderful talks! We’re in a “fear of quinolones” era, and so are loathe to give prolonged courses, especially to the elderly, unless absolutely needed. I saw that the median age of the participants was roughly in their 30s. Do you feel the trial had enough older patients to address these FQ concerns?
do you want to say something? Gustavo is asking
I’m happy to ask Eric’s question next-
gustavo can you do paul’s or invite him
Yes I’ll take Paul’s. He put his hand down before so I will read it out. We are close to the hour, will be go to 5 minutes after?
Paul, Rocio is asking to engage you. are you willing?
Any concern for vulnerability to baseline resistance compared to RIPE? If INH or fluoroquinolone resistance at baseline? Need for testing beyond rif?
i can ask Karen Jacobson’s q
Wrong Paul enabled- can you enable Paul Sax?
Paul Sax not Converse
sorry paul, i meant to engage the other paul.
Thanks, No problem!
Rocio, Karen’s then close?
Rocio we’ll defer to you to do the closure after the answer to this question.
ok if no more then i can close